D-Ribose is a natural pentose sugar that is the backbone of the ATP molecular structure, which supports the body’s natural energy production. D-Ribose chewable tablets have a great-tasting, natural vanilla flavor, are sweetened with xylitol, and are convenient for on-the-go supplementation.
Corvalen® Chews are all-natural D-ribose supplements clinically studied to help restore and replenish core
energy. D-ribose is a natural pentose sugar that supports cardiovascular health, promotes energy production
and mitochondrial function, and improves recovery and performance after exercise.
• Support for cellular ATP energy production‡
• Mitochondrial support‡
FUNCTIONS AND MECHANISM OF ACTION
D-ribose is a naturally occurring monosaccharide that is found in all cells and is involved in mitochondrial
energy production. D-ribose is a substrate of the adenosine triphosphate (ATP) molecule, which is responsible
for proper cell function and maintenance, including the synthesis of DNA and RNA. The pentose phosphate
pathway (PPP) forms ribose-5-phosphate to ultimately produce ATP. This process is slow, as it requires a ratelimiting enzyme called glucose-6-phosphate dehydrogenase (G6PD). Alternatively, supplemental D-ribose may
bypass the need for G6PD via purine metabolism, which occurs in the mitochondria. This process is more
efficient, as it enables cells to efficiently reuse ATP metabolites to form new ATP molecules.
D-ribose plays a critical role in energy metabolism by restoring and enhancing ATP concentrations. Clinical
studies have shown that supplementation with D-ribose improved blood flow and enhanced the recovery rate of
ATP synthesis, thus restoring cardiac energy metabolism. Following exercise, skeletal muscle ATP levels are
depleted and may impact recovery time and subsequent performance. Supplemental D-ribose has been shown
to restore tissue energy levels and improve recovery and performance in humans. The involvement of ribose in
mitochondrial energy production may also indicate a supportive role of D-ribose in overall mitochondrial
function and quality.