N-Acetyl-L-Cysteine vegetarian capsules, provided by Douglas Laboratories, contain 500 mg pure N-Acetyl-L-Cysteine. N-Acetyl-L-Cysteine is a biologically active precursor for the amino acid cysteine which, in turn, is a precursor for glutathione, a tripeptide with antioxidant properties.
Body cells and tissues are threatened continuously by damage caused by toxic free radicals and reactive
oxygen species (e.g., peroxides) which are produced during normal oxygen metabolism, by other chemical
reactions, and by toxic agents in the environment. Free radicals, once formed, are capable of disrupting
metabolic activity and cell structure. When this occurs, additional free radicals are produced which, in turn,
can result in more extensive damage to cells and tissues. The uncontrolled production of free radicals is
thought to be a major contributing factor to many degenerative diseases.
N-Acetyl-L-Cysteine is a precursor for the sulfur amino acid cysteine, and cysteine is used by the body to
synthesize glutathione. Glutathione is a naturally occurring tripeptide which is a major component of two antifree radical enzymes - glutathione peroxidase and glutathione reductase. As such, glutathione offers one
mechanism for scavenging toxic free radicals and inhibiting peroxidation thereby slowing down free-radical
catalyzed chain reactions. Glutathione per se is well absorbed in the intestine, and enters the blood and other
extracellular compartments where it exerts much of its beneficial antioxidant effects. However, it can not
effectively enter the cell.
In contrast to glutathione, N-Acetyl-L-Cysteine is efficiently transported into the cell where it is readily
converted to cysteine for glutathione synthesis. Thus, supplementation with N-Acetyl-L-Cysteine can raise
intracellular glutathione levels.
Providing supplemental cysteine to elevate intracellular glutathione levels is generally not advised due to
cysteine’s inherent toxicity. N-Acetyl-L-Cysteine is virtually non-toxic and well absorbed, which is why
supplementation with N-Acetyl-L-Cysteine is recognized as a safe, highly effective method of increasing
intracellular glutathione stores.
Aside from providing cysteine as a glutathione precursor, N-Acetyl-L-Cysteine also appears to have antioxidant
properties as such, and is a valuable sulfur donor for various metabolic needs.
‡These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
N-ACETYL CYSTEINE 500 MG